Allopurinol Price

 

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allopurinol 300 mg price

Allopurinol is used for treating gout caused by excessive levels of uric acid in the blood (hyperuricemia). It is a xanthine oxidase inhibitor and is similar to febuxostat (Uloric). Uric acid is a by product from the breakdown of certain proteins (purines) in the body by enzymes called xanthine oxidases. Hyperuricemia occurs when the body produces more uric acid than it can eliminate. The uric acid forms crystals in joints (gouty arthritis) and tissues, causing inflammation and pain. Elevated blood uric acid levels also can cause kidney disease and kidney stones. Allopurinol prevents the production of uric acid by blocking the activity of the enzymes that converts purines to uric acid. Uric acid levels usually begin to fall within 2-3 days of starting treatment and return to their original Allopurinol can lower blood cells that help your body fight infections. This can make it easier for you to bleed from an injury or get sick from being around others who are ill. Your blood may need to be tested often. Visit your doctor regularly. Avoid drinking alcohol. It can make your condition worse. Pharmacological action: Allopurinol - a drug that violates the synthesis of uric acid. Allopurinol and its main derivative oksipurinola have urostaticheskoe action. The mechanism of action of allopurinol related to its ability to inhibit the activity of the enzyme xanthine oxidase, which catalyzes the oxidation of hypoxanthine to xanthine and its further transformation into uric acid. Violating thus the synthesis of uric acid, allopurinol reduces its levels in the body, and promotes the dissolution of urate. When administered allopurinol is well absorbed in the digestive tract, reaching peak plasma concentrations within 1.5 hours (peak plasma concentration of primary metabolite observed after 3-5 hours after administration).